  Original Papers  |
| 2022 |
1. Masuda A, Lee J, Miyata T, Mon H, Sato K, Oyama K, Sakurai Y, Yasuda J, Takahashi D, Ueda T, Kato Y, Nishida M, Karasaki N, Kakino K, Ebihara T, Nagasato T, Hino M, Nakashima A, Suzuki K, Tonooka Y, Tanaka M, Moriyama T, Nakatake H, Fujita R, Kusakabe T., Optimization of SARS-CoV2 Spike protein expression in the silkworm and induction of efficient protective immunity by inoculation with alum adjuvants., Front. Immunol., 2022.1.
2. Nishiyama K, Nishimura A, Shimoda K, Tanaka T, Kato Y, Shibata T, Tanaka
H, Kurose H, Azuma YT, Ihara H, Kumagai Y, Akaike T, Eaton P, Uchida K,
Nishida M. Redox-dependent internalization of purinergic P2Y6 receptor
limits colitis progression. Science Signaling. 2022. 15(716):eabj0644
3. Shimauchi T, Numaga-Tomita T, Kato Y, Morimoto H, Sakata K, Matsukane
R, Nishimura A, Nishiyama K, Shibuta A, Horiuchi Y, Kurose H, Kim SG, Urano
Y, Ohshima T, Nishida M. A TRPC3/6 Channel Inhibitor Promotes Arteriogenesis
after Hind-Limb Ischemia. Cells. 2022. 11(13):2041.
4. Numaga-Tomita T, Shimauchi T, Kato Y, Nishiyama K, Nishimura A, Sakata K, Inada H, Kita S, Iwamoto T, Nabekura J, Birnbaumer L, Mori Y, Nishida M. Inhibition of transient receptor potential cation channel 6 promotes capillary arterialization during post-ischaemic blood flow recovery. Br J Pharmacol. 2022.
5. Hirata N, Yamada S, Yanagida S, Ono A, Yasuhiko Y, Nishida M, Kanda Y. Lysophosphatidic acid promotes the expansion of cancer stem cells via TRPC3 channels in triple-negative breast cancer. Int. J. Mol. Sci. 2022, 23(4), 1967. doi: 10.3390/ijms23041967.
6. Murata R, Watanabe H, Nosaki H, Nishida K, Maeda H, Nishida M, Maruyama
T. Long-acting thioredoxin ameliorates doxorubicin-induced cardiomyopathy
via its anti-oxidative and antiinflammatory action. Pharmaceutics 2022
14(3), 562. doi: 10.3390/pharmaceutics14030562.
7. Iwata Y, Nakade Y, Kitajima S, Yoneda-Nakagawa S, Oshima M, Sakai N,
Ogura H, Sato K, Toyama T, Yamamura Y, Miyagawa T, Yamazaki H, Hara A,
Shimizu M, Furuichi K, Mita M, Hamase K, Tanaka T, Nishida M, Muramatsu
W, Yamamoto H, Shichino S, Ueha S, Matsushima K, Wada T. Protective effect
of d-alanine against acute kidney injury. Am J Physiol Renal Physiol. 2022
Jun 1;322(6):F667-F679. doi: 10.1152/ajprenal.00198.2021.
8. Yamada S, Noda T, Okabe K, Yanagida S, Nishida M, Kanda Y. SARS-CoV-2 induces barrier damage and inflammatory responses in the human iPSCderived intestinal epithelium. J Pharmacol Sci. 2022 Jul;149(3):139-146. doi: 10.1016/j.jphs.2022.04.010.
9. Tokuyama T, Uosaki H, Sugiura A, Nishitai G, Takeda K, Nagashima S,
Shiiba I, Ito N, Amo T, Mohri S, Nishimura A, Nishida M, Konno A, Hirai
H, Ishido S, Toshizawa T, Shindo T, Takada T, Kinugawa S, Inatome R and
Yanagi S, Protective roles of MITOL against myocardial senescence and ischemic
injury partly via Drp1 regulation. iScience, 2022, 25:14582
10. Akiyama M, Unoki T, Aoki H, Nishimura A, Shinkai Y, Warabi E, Nishiyama
K, Furumoto Y, Anzai N, Akaike T, Nishida M, Kumagai Y, Cystine-dependent
antiporters buffer against excess intracellular reactive sulfur species-induced
stress. Redox Biology 2022 57:102514.
11. Oda S, Nishiyama K, Furumoto Y, Yamaguchi Y, Nishimura A, Tang X, Kato Y, Numaga-Tomita T, Kaneko T, Mangmool S, Kuroda T, Okubo R, Sanbo M, Hirabayashi M, Sato Y, Nakagawa Y, Kuwahara K, Nagata R, Iribe G, Mori Y, Nishida M. Myocardial TRPC6-mediated Zn2+ influx induces beneficial positive inotropy through - adrenoceptors. Nature Communications. 2022, 13(1):6374.
12. Kato Y, Nishiyama K, Lee JM, Ibuki Y, Imai Y, Noda T, Kamiya N, Kusakabe
T, Kanda Y, Nishida M*. TRPC3-Nox2 protein complex formation increases
the risk of SARS-CoV-2 Spike proteininduced cardiomyocyte dysfunction
through ACE2 upregulation. Int. J. Mol. Sci. 2023, 24, 102. https://doi.org/10.3390/ijms24010102. |
| 2021 |
1. Yagi-Utsumi M, Tanaka T, Otsubo Y, Yamashita A, Yoshimura S, Nishida
M, Kato K. Cold Atmospheric Plasma Modification of Amyloid β. Int J Mol
Sci. 2021 Mar; 22(6): 3116. doi: 10.3390/ijms22063116.
2. Marutani E, Morita M, Hirai S, Kai S, Grange R, Miyazaki Y, Nagashima F, Traeger L, Magliocca A, Ida T, Matsunaga T, Flicker D, Corman B, Mori N, Yamazaki Y, Batten A, Li R, Tanaka T, Ikeda T, Nakagawa A, Atochin D, Ihara H, Olenchock B, Shen X, Nishida M, Hanaoka K, Kevil C, Xian M, Bloch D, Akaike T, Hindle A, Motohashi H, and Ichinose F. Sulfide catabolism ameliorates hypoxic brain injury. Nature Commun. 2021; 12: 3108. doi: 10.1038/s41467-021-23363-x.
3. Matsuoka Y, Takahashi M, Sugiura Y, Izumi Y, Nishiyama K, Nishida M,
Suematsu M, Bamba T, Yamada KI. Structural library and visualization of
endogenously oxidized phosphatidylcholines using mass spectrometry-based
techniques. Nature Commun. 2021;12(1):6339. doi: 10.1038/s41467- 021-26633-w.
4. Nishiyama K, Nishimura A, Shimoda K, Tanaka T, Kato Y, Shibata T, Tanaka
H, Kurose H, Azuma YT, Ihara H, Kumagai K, Akaike T, Eaton P, Uchida K,
Nishida M*. Redox-dependent internalization of purinergic P2Y6 receptor
limits colitis progression. Science Signal. 2022 Jan 11;15(716):eabj0644.
doi: 10.1126/scisignal.abj0644. |
| 2020 |
1. Shimoda K, Nishimura A, Sunggip C, Ito T, Nishiyama K, Kato Y, Tanaka
T, TOzakisaitoh H, Tsuda M, Nishida M.
Modulation of P2Y6R expression exacerbates pressure overload-induced cardiac
remodeling in mice.
Sci Rep. 2020 Aug 18;10(1):13926. doi: 10.1038/s41598-020-70956-5.
2. Shiratori-Hayashi M, Yamaguchi C, Eguchi K, Shiraishi Y, Kohno K, Mikoshiba
K, Inoue K, Nishida M, Tsuda M.
Astrocytic STAT3 activation and chronic itch require IP3R1/TRPC-dependent
Ca2+ signals in mice.
J Allergy Clin Immunol. 2020 Aug 8;S0091-6749(20)31105-2. doi: 10.1016/j.jaci.2020.06.039.
3. Nishiyama K, Toyama C, Kato Y, Tanaka T, Nishimura A, Nagata R, Mori Y, Nishida M.
Deletion of TRPC3 or TRPC6 fails to attenuate the formation of inflammation
and fibrosis in non-alcoholic steatohepatitis.
Biol Pharm Bull. 2021;44(3):431-436. doi: 10.1248/bpb.b20-00903.
4. Azuma YT, Suzuki S, Nishiyama K, Yamaguchi T. Gastrointestinal motility modulation by stress is
associated with reduced smooth muscle contraction through specific transient receptor potential channel. J
Vet Med Sci. 2021 Apr 9;83(4):622-629. doi: 10.1292/jvms.20-0490
5. Azuma YT and Nishiyama K. Interleukin-19 Enhances Cytokine Production Induced by
Lipopolysaccharide and Inhibits Cytokine Production Induced by polyI:C in BALB/c Mice. The Journal of
veterinary medical science. 2020. 82(7):891-896. doi: 10.1292/jvms.20-0137
6. Che J, Yamaji N, Miyaji T, Miyani-Ueno N, Kato Y, Shen F R, Ma F J.
Node-localized transporters of phosphorus essetial for seed development in rice.
Plant Cell Physiol. 2020 Aug 1;61(8):1387-1398. doi: 10.1093/pcp/pcaa074. |
| 2019 |
Suhaini Sudi, Tomohiro Tanaka, Sayaka Oda, Kazuhiro Nishiyama, Akiyuki Nishimura, Caroline Sunggip, Supachoke Mangmool, Takuro Numaga-Tomita, and Motohiro Nishida
TRPC3-Nox2 axis mediates nutritional deficiency-induced cardiomyocyte atrophy.
Scientific Reports 05 June 2019 DOI:10.1038/s41598-019-46252-2
|
Nishiyama K, Numaga-Tomita T, Fujimoto Y, Tanaka T, Toyama C, Nishimura A, Yamashita T, Matsunaga N, Koyanagi S, Azuma YT, Ibuki Y, Uchida K, Ohdo
S, Nishida M
Ibudilast attenuates doxorubicin-induced cytotoxicity by suppressing formation
of TRPC3-Nox2 protein complexs.
Br J Pharmacol. 2019 Sep;176(18):3723-3738. doi: 10.1111/bph.14777. Epub 2019 Aug 6.
Nisimura A, SHimoda K, Tanaka T, Toyama C, Nishiyama K, Shinkai Y, Numaga-Tomita T, Yamazaki D, Kanda Y, Akaike T, Kumagai Y
and Nishida M.
Depolysulidation of Drp1 induced by low-dose methylmercury exposure increases
cardiac vulnerability to hemodynamic overload
Science Signaling DOI: 10.1096/fj.201802811R.
|
Numaga-Tomita T, Shimauchi T, Oda S, Tanaka T, Nishiyama K, Nishimura
A , Birnbaumer L., Mori Y., and Nishida M.
TRPC6 regulates phenotypic switching of vascular smooth muscle cells through
plasma membrane potential-dependent coupling with PTEN.
The FASEB Journal 2019 Sep;33(9):9785-9796. DOI: 10.1096/fj.201802811R.
|
| |
| 2018 |
Masuda K, Tsutsuki H, Kasamatsu S, Ida T, Takata T, Sugiura K, Nishida
M, Watanabe Y, Sawa T, Akaike T, Ihara H. (2018)
Involvement of nitric oxide/reactive oxygen species signaling via 8-nitro-cGMP
formation in 1-methyl-4-phenylpyridinium ion-induced neurotoxicity in PC12
cells and rat cerebellar granule neurons.
Biochem Biophys Res Commun. Jan 15;495(3):2165-2170. doi: 10.1016/j.bbrc.2017.12.088.
|
Sunggip C, Shimoda K, Oda S, Tanaka T, Nishiyama K, Mangmool S, Nishimura
A, Numaga-Tomita A, Nishida M. (2018)
TRPC5-eNOS axis negatively regulates ATP-induced cardiomyocyte hypertrophy.
Front. Pharmacol. May 22;9:523. doi: 10.3389/fphar.2018.00523.
|
Nishimura A, Shimauchi T, Tanaka T, Shimoda K, Toyama T, Kitajima
N, Ishikawa T, Shindo N, Numaga-Tomita T, Yasuda S, Sato Y, Kuwahara K,
Kumagai Y, Akaike T, Ide T, Ojida A, Mori Y, Nishida M. (2018)
Hypoxia-induced interaction of filamin with Drp1 causes mitochondrial hyperfission-associated
myocardial senescence.
Science Signaling Nov 13;11(556). pii: eaat5185. doi: 10.1126/scisignal.aat5185.
|
Parichatikanond W, Nishimura A, Nishida M, Mangmool S. (2018)
Prolonged stimulation of β2-adrenergic receptor with β2-agonists impairs
insulin actions in H9c2 cells.
J. Pharmacol. Sci. Nov;138(3):184-191. doi: 10.1016/j.jphs.2018.09.007.
|
Ihara H, Kakihana Y, Yamakage A, Kai K, Shibata T, Nishida M, Yamda
KI, Uchida K. (2018)
2-Oxo-histidine-containing dipeptides are functional oxidation products.
J. Biol. Chem. Nov 30. pii: jbc.RA118.006111. doi: 10.1074/jbc.RA118.006111.
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| 2017 |
Oda S., Numaga-Tomita T., Kitajima N., Toyama T., Harada E., Shimauchi
T., Nishimura A., Ishikawa T., Kumagai Y., Birnbaumer L. and Nishida M.
TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of
hyperglycemia-induced heart failure in mice.
Sci. Rep. Aug 8;7(1):7511 (2017). doi: 10.1038/s41598-017-07903-4.
|
Phosri S., Arieyawong A., Boonrukchai K., Parichatikanond W.,
Nishimura A., Nishida M. and Mangmool S.
Stimulation of adenosine A2B receptor inhibits endothelin-1-induced cardiac fibroblast proliferation
and α-smooth muscle actin synthesis through the cAMP/Epac/PI3K/Akt-signaling
pathway.
Front. Pharmacol. Jun 30;8:428 (2017). doi: 10.3389/fphar.2017.00428.
|
Shimauchi T., Numaga-Tomita T., Ito T., Nishimura A., Matsukane R.,
Oda S, Hoka S., Ide T., Koitabashi N., Uchida K., Sumimoto H., Mori Y.
and Nishida M.
TRPC3-Nox2 complex mediates doxorubicin-induced myocardial atrophy.
JCI Insight. Aug 3;2(15). pii: 93358 (2017). doi: 10.1172/jci.insight.93358.
|
Nakagawa Y, Nishikimi T, Kuwahara K, Fujishima A, Oka S, Tsutamoto
T, Kinoshita H, Nakao K, Cho K, Inazumi H, Okamoto H, Nishida M, Kato T,
Fukushima H, Yamashita JK, Wijnen WJ, Creemers EE, Kangawa K, Minamino
N, Nakao K, Kimura T.
MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts.
J Am Heart Assoc. Feb 10;6(2), pii: e003601 (2017). doi: 10.1161/JAHA.116.003601.
|
Yamaguchi Y, Iribe G, Kaneko T, Takahashi K, Numaga-Tomita T, Nishida
M, Birnbaumer L, Naruse K.
TRPC3 participates in angiotensin II type 1 receptor-dependent stress-induced
slow increase in intracellular Ca2+ concentration in mouse cardiomyocytes.
J. Physiol. Sci. Jan 19 (2017). doi: 10.1007/s12576-016-0519-3.
|
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| 2016 |
Numaga-Tomita T., Kitajima N., Kuroda T., Nishimura A., Miyano K.,
Yasuda S., Kuwahara K., Sato Y., Ide T., Birnbaumer L., Sumimoto H., Mori
Y. and Nishida M.
TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis.
Sci. Rep. 6, 39383 (2016); doi: 10.1038/srep39383.
|
Kitajima N., Numaga-Tomita T., Watanabe M., Kuroda T., Nishimura
A., Miyano K., Yasuda S., Kuwahara K., Sato Y., Ide T., Birnbaumer L.,
Sumimoto H., Mori Y. and Nishida M.
TRPC3 positively regulates reactive oxygen species driving maladaptive
cardiac remodeling.
Sci. Rep. 6, 37001 (2016). doi: 10.1038/srep37001.
|
Unoki T, Abiko Y, Toyama T, Uehara T, Tsuboi K, Nishida M, Kaji T,
Kumagai Y.
Methylmercury, an environmental electrophile capable of activation and
disruption of the Akt/CREB/Bcl-2 signal transduction pathway in SH-SY5Y
cells.
Sci Rep., Jun 30;6:28944 (2016). doi: 10.1038/srep28944.
|
Hagimori M, Murakami T, Shimizu K, Nishida M, Ohshima T, Mukai T.
Synthesis of radioiodinated probes to evaluate the biodistribution of a
potent TRPC3 inhibitor.
Med. Chem. Comm. 7(5), 1003-1006 (2016). doi: 10.1039/c6md00023a.
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Nishimura A, Sunggip C, Tozaki-Saitoh H, Shimauchi T, Numaga-Tomita
T, Hirano K, Ide T, Boeynaems J-M, Kurose H, Tsuda M, Robaye B, Inoue K,Nishida
M*.
The purinergic P2Y6 receptor heterodimerizes with the angiotensin AT1 receptor to promote
angiotensin II-induced hypertension.
Sci. Signal. 9(411), ra7 (2016). doi: 10.1126/scisignal.aac9187.
|
Sawamura S, Hatano M, Takada Y, Hino K, Kawamura T, Tanikawa J, Nakagawa
H, Hase H, Nakao A, Hirano M, Rotrattanadumrong R, Kiyonaka S, Mori MX,
Nishida M, Hu Y, Inoue R, Nagata R, Mori Y.
Screening of Transient Receptor Potential Canonical Channel Activators
Identifies Novel Neurotrophic Piperazine Compounds.
Mol Pharmacol. 89(3), 348-363 (2016). doi: 10.1124/mol.115.102863.
|
Mangmool S, Denkaew T, Phosri S, Pinthong D, Parichatikanond W, Shimauchi
T, Nishida M.
Sustained βAR stimulation mediates cardiac insulin resistance in a PKA-dependent
manner.
Mol Endocrinol. 30(1), 118-132 (2016). doi: 10.1210/me.2015-1201.
|
Numaga-Tomita T, Nishida M*, Putney JW Jr. and Mori Y*.
TRPC3 amplifies B cell receptor-induced ERK signaling via protein kinase
D-dependent Rap1activation.
Biochem J. Jan 15;473(2):201-10 (2016). doi: 10.1042/BJ20150596. (*corresponding author)
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| 2015 |
Gentry LR, Nishimura A, Cox AD, Martin TD, Tsygankov D, Nishida M,
Elston TC, Der CJ.
Divergent Roles of CAAX Motif-signaled Posttranslational Modifications
in the Regulation and Subcellular Localization of Ral GTPases.
J Biol Chem. 290(37), 22851-22861 (2015). doi: 10.1074/jbc.M115.656710.
|
Shinkai Y, Abiko Y, Ida T, Miura T, Kakehashi H, Ishii I, Nishida
M, Sawa T, Akaike T, Kumagai Y.
Reactive Sulfur Species-Mediated Activation of the Keap1-Nrf2 Pathway by
1,2-Naphthoquinone through Sulfenic Acids Formation under Oxidative Stress.
Chem Res Toxicol. 28(5), 838-847 (2015). doi: 10.1021/tx500416y.
|
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| 2014 |
Yamada Y, Kinoshita H, Kuwahara K, Nakagawa Y, Kuwabara Y, Minami
T, Yamada C, Shibata J, Nakao K, Cho K, Arai Y, Yasuno S, Nishikimi T,
Ueshima K, Kamakura S, Nishida M, Kiyonaka S, Mori Y, Kimura T, Kangawa
K, Nakao K.
Inhibition of N-type Ca2+ channels ameliorates an imbalance in cardiac autonomic nerve activity and prevents lethal arrhythmias in mice with heart failure.
Cardiovasc. Res. 104(1):183-93 (2014). doi: 10.1093/cvr/cvu185.
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| 2013 |
Watari K, Nakaya M, Nishida M, Kim KM, Kurose H.
β-arrestin2 in infiltrated macrophages inhibits excessive inflammation
after myocardial infarction.
PLoS One. 8(7):e68351 (2013). doi: 10.1371/journal.pone.0068351.
|
Nakaya M, Tajima M, Kosako H, Nakaya T, Hashimoto A, Watari K, Nishihara
H, Ohba M, Komiya S, Tani N, Nishida M, Taniguchi H, Sato Y, Matsumoto
M, Tsuda M, Kuroda M, Inoue K, Kurose H. GRK6 deficiency in mice
causes autoimmune disease due to impaired apoptotic cell clearance.
Nature Commun. 4, 1532 (2013). doi: 10.1038/ncomms2540.
|
Nishida M, Ishikawa T, Saiki S, Sunggip C, Aritomi S, Harada
E, Kuwahara K, Hirano K, Mori Y, Kim-Mitsuyama S.
Voltage-dependent N-type Ca2+ channels in endothelial cells contribute to oxidative stress-related endothelial
dysfunction induced by angiotensin II in mice.
Biochem. Biophys. Res. Commun. 434(2), 210-216 (2013). doi: 10.1016/j.bbrc.2013.03.040.
|
Chen W, Oberwinkler H, Werner F, Gasner B, Nakagawa H, Feil R, Hofmann
F, Schlossmann J, Dietrich A, Gudermann T, Nishida M, Del Galdo S, Wieland
T, Kuhn M.
Atrial natriuretic peptide-mediated inhibition of microcirculatory endothelial
Ca2+ and permeability response to histamine involves cGMP-dependent protein
kinase I and TRPC6 channels.
Arterioscler. Thromb. Vasc. Biol. 33(9), 2121-2129 (2013). doi: 10.1161/ATVBAHA.113.001974.
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| 2012 |
Nakaya M, Chikura S, Watari K, Mizuno N, Mochinaga K, Mangmool
S, Koyanagi S, Ohdo S, Sato Y, Ide T, Nishida M, Kurose H.
Induction
of cardiac fibrosis by β-blocker in G protein-independent and
GRK5/β-arrestin2-dependent signaling pathways.
J. Biol. Chem. 2012 Oct 12;287(42):35669-35677. doi: 10.1074/jbc.M112.357871.
|
Nakaya M, Chikura S, Watari K, Mizuno N, Mochinaga K, Mangmool
S, Koyanagi S, Ohdo S, Sato Y, Ide T, Nishida M, Kurose H.
Induction
of cardiac fibrosis by β-blocker in G protein-independent and
GRK5/β-arrestin2-dependent signaling pathways.
J. Biol. Chem. 2012 Oct 12;287(42):35669-35677. doi: 10.1074/jbc.M112.357871.
|
Fujino T, Ide T, Yoshida M, Onitsuka K, Tanaka A, Hata Y, Nishida
M, Takehara T, Kanemaru T, Kitajima N, Takazaki S, Kurose H, Kang D, Sunagawa
K.
Recombinant
mitochondrial transcription factor A protein inhibits nuclear factor of
activated T cells signaling and attenuates pathological hypertrophy of cardiac
myocytes.
Mitochondrion. 12:449-458(2012). Epub 2012 Jun 16. doi: 10.1016/j.mito.2012.06.002
|
Nishida M, Sawa T, Kitajima N, Ono K, Inoue H, Ihara H, Motohashi
H, Yamamoto M, Suematsu M, Kurose H, van der Vliet A, Freeman BA, Shibata
T, Uchida K, Kumagai Y, Akaike T.
Hydrogen
sulfide anion regulates redox signaling via electrophile sulfhydration.
Nature Chem Biol. 8: 714-724 (2012) doi: 10.1038/nchembio.1018. [Epub ahead of print]
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| English Reviews |
| |
Sawa T, Ono K, Tsutsuki H, Zhang T, Ida T, Nishida M, Akaike T. (2018)
Reactive Cysteine Persulphides: Occurrence, Biosynthesis, Antioxidant Activity,
Methodologies, and Bacterial Persulphide Signalling.
Adv Microb Physiol. 72:1-28. doi: 10.1016/bs.ampbs.2018.01.002.
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Numaga-Tomita T, Oda S, Nishiyama K, Tanaka T, Nishimura A, Nishida
M. (2018)
TRPC channels in exercise-mimetic therapy.
Pflügers Archiv – Eur. J. Physiol. Oct 8. doi: 10.1007/s00424-018-2211-3.
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Yamaguchi Y, Iribe G, Nishida M and Naruse K.
Role of TRPC3 and TRPC6 channels in the myocardial response to stretch: Linking physiology and pathophysiology.
Prog Biophys Mol Biol. Jun 20. pii: S0079-6107(17)30023-8 (2017).
doi: 10.1016/j.pbiomolbio.2017.06.010. [Epub ahead of print] Review.
|
Nishimura A, Sunggip C, Oda S, Numaga-Tomita T, Tsuda M and Nishida
M.
Purinergic P2Y receptors: Molecular diversity and implications for treatment
of cardiovascular diseases. Pharmacol Ther. Jun 22. pii: S0163-7258(17)30158-4
(2017). doi: 10.1016/j.pharmthera.2017.06.010. [Epub ahead of print] Review.
|
Sunggip C, Nishimura A, Shimoda K, Numaga-Tomita T, Tsuda M and Nishida
M.
Purinergic P2Y6 receptors: A new therapeutic target of age-dependent hypertension.
Pharmacol Res. 2017 Jun;120:51-59. doi: 10.1016/j.phrs.2017.03.013. Epub 2017 Mar 20. Review.
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Nishida M, Nishimura A, Matsunaga T, Motohashi H, Kasamatsu S and
Akaike T.
Redox regulation of electrophilic signaling by reactive persulfides in
cardiac cells.
Free Radic Biol Med. pii: S0891-5849(17)30033-3, 2017. doi: 10.1016/j.freeradbiomed.2017.01.024.
|
Fujii S, Sawa T, Nishida M, Ihara H, Ida T, Motohashi H, and Akaike
T.
Redox signaling regulated by an electrophilic cyclic nucleotide and reactive
cysteine persulfides.
Arch Biochem Biophys.;595:140-146 (2016). doi: 10.1016/j.abb.2015.11.008
|
Nishida M, Kumagai Y, Ihara H, Fujii S, Motohashi H, Akaike T.
Redox signaling regulated by electrophiles and reactive sulfur species.
J. Clin. Biochem. Nutr. 58(2):91-98 (2016). doi: 10.3164/jcbn.15-111.
|
Nishida M*, Toyama T, Akaike T.
Role of 8-nitro-cGMP and its redox regulation in cardiovascular electrophilic
signaling.
J Mol Cell Cardiol. 73, 10-7 (2014). doi: 10.1016/j.yjmcc.2014.02.003.
|
Sawa T, Ihara H, Ida T, Fujii S, Nishida M, Akaike T.
Formation, signaling functions, and metabolisms of nitrated cyclic nucleotide.
Nitric Oxide 34, 10-18 (2013). doi: 10.1016/j.niox.2013.04.004.
|
Akaike T, Nishida M, Fujii S.
Regulation of redox signalling by an electrophilic cyclic nucleotide.
J. Biochem. 153(2), 131-138 (2013). doi: 10.1093/jb/mvs145.
|
Sunggip C, Kitajima N, Nishida M.
Redox control of cardiovascular homeostasis by angiotensin II.
Curr Pharm Des. 19(17), 3022-3032 (2013)
|
Akaike T, Nishida M, Fujii S.
Regulation of redox signaling by an electrophilic cyclic nucleotide.
J Biochem. 153(2), 131-138 (2013). doi: 10.1093/jb/mvs145.
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Nishida M, Sunggip C, Kitajima N & Kurose H
Redox
regulation of angiotensin receptor signaling in the heart.
Angiotensin: New Research, NOVA Publishers (New York) (2012).
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019.gif) English Books /Desktop/心循環シグナルHP２/a_line019.gif) |
Nishida M, Kuwahara K, Kozai D, Sakaguchi R, Mori Y.
TRP Channels: Their Function and Potentiality as Drug Targets.
Innovative Medicine: Basic Research and Development (Springer Open, edited
by Nakao K, Minato N and Uemoto S), ISBN 978-4-431-55651-0 (eBook) 195-218
(2015). DOI 10.1007/978-4-431-5561-0_17.
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Nishida M*, Sunggip C, Kitajima N & Kurose H
Redox regulation of angiotensin receptor signaling in the heart.
Angiotensin: New Research, NOVA Publishers (New York), Edited by Harada
S and Moi I. 165-179 (2012).
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| 和文総説・著書(Japanese Reviews and Books) |
西村明幸、西田基宏 (2018)
活性イオウによる心筋早期老化制御
DOJIN NEWS 165: 1-5.
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西田基宏、西村明幸、西山和宏、田中智弘 (2018)
活性イオウによるミトコンドリア品質管理と心疾患リスク制御
硫酸と工業 71(5): 65-72
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小田紗矢香、下田翔、冨田拓郎、西田基宏 (2018)
アントラサイクリンによる心筋傷害のメカニズムUPDATE
循環器内科 83(6): 554-559.
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西田基宏、西村明幸、下田翔 (2018)
活性イオウによるミトコンドリア機能制御
実験医学 36(5): 663-668
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小田紗矢香、冨田拓郎、西田基宏 (2018)
運動模倣薬の新たなストラテジー
YAKUGAKU ZASSHI 138(10): 1257-1262.
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西田基宏、西村明幸、西山和宏 (2018)
心臓リモデリングを制御するGタンパク質／受容体シグナリング
日本臨牀増刊「心不全（第2版） 上巻－最新の基礎・臨床研究の進歩－」 76(9)
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島内司、西村明幸、石川達也、西田基宏
ミトコンドリア分裂を主眼とした既承認薬のエコファーマ
日本薬理学雑誌 149, 269-273, 2017.
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西村明幸、西田基宏
プリン作動性P2Y6受容体はアンジオテンシンAT1受容体とヘテロ二量体化を形成してアンジオテンシンII誘発性高血圧を促進する
Japanese Scientists in Science Signaling 2016「シグナリングに載った日本人研究者」 2017 Issue (Science Signaling AAAS, Cosmo Bio Co. Inc.)．
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西村明幸、西田基宏
プリン作動性シグナルの心血管系における役割
日本薬理学雑誌 149, 84－90, 2017.
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西田基宏、島内司
ガス様シグナルの破綻と疾患
医学のあゆみ（2015年8月号）
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西田基宏、西村明幸
酸素シグナル
実験医学（2015年6月増刊号）
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西田基宏、森泰生
Ｇタンパク質、ＴＲＰシグナルと活性イオウ分子
細胞工学（2015年4月特集号）
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森泰生、森誠之、西田基宏
カルシウムシグナルの基本機構とその可能性 Clin Calcium. 25(1):47-58. doi: CliCa15014758. Review.
Japanese.（2015年1月）．
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Nishida M, Toyama T, Kumagai Y, Numaga-Tomita T.
Establishment of a novel therapeutic strategy for heart failure based
on the mechanism underlying maintenance of redox homeostasis by reactive
sulfur species.
Yakugaku Zasshi. 134(12):1239-1243 (2014).
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北島直幸、西田基宏
心臓におけるTRPチャネルの多様な役割
実験医学 Vol.32, No.4, 527-533 (2014).
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西田基宏
酸化ストレスによるレドックス恒常性異常と心筋リモデリング
医学のあゆみ Vol. 247, No. 9, 875-878 （2013）.
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西田基宏，角田将明，北島直幸
TRPチャネルの生理機能と病態生理
Clinical Calcium 23(4), 561-568 (2013).
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北島直幸，西田基宏
硫化水素のケミカルバイオロジー
日薬理誌 Vol. 141, 350-351 (2013).
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西田基宏，澤智裕
硫化水素アニオンによるレドックス恒常性制御とその臨床応用
生化学 みにれびゅー Vol. 85, No. 11, 996-999 （2013）
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